Measurement of relative lung perfusion with electrical impedance and positron emission tomography: an experimental comparative study in pigs.

ABSTRACT:

Background

Electrical impedance tomography (EIT) with indicator dilution may be clinically useful to measure relative lung perfusion, but there is limited information on the performance of this technique.

Methods

Thirteen pigs (50-66 kg) were anaesthetised and mechanically ventilated. Sequential changes in ventilation were made: (i) right-lung ventilation with left-lung collapse, (ii) two-lung ventilation with optimised PEEP, (iii) two-lung ventilation with zero PEEP after saline lung lavage, (iv) two-lung ventilation with maximum PEEP (20/25 cm H₂O to achieve peak airway pressure 45 cm H₂O), and (v) two-lung ventilation under unilateral pulmonary artery occlusion. Relative lung perfusion was assessed with EIT and central venous injection of saline 3%,

SUBMITTER: Bluth T 

PROVIDER: S-EPMC6676171 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature