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Risk prediction for severe disease and better diagnostic accuracy in early dengue infection; the Colombo dengue study.


ABSTRACT:

Background

A major challenge in dengue management in resource limited settings is the confirmation of diagnosis. Clinical features of dengue often overlap with other infections and molecular diagnostic tools are not readily accessible to clinicians at hospitals. In addition, the prediction of plasma leakage in dengue is also difficult. Hematocrit level and ultrasound scans (combined with clinical parameters) are helpful to detect plasma leakage once it has happened, not before.

Methods

Colombo Dengue Study (CDS) is a prospective cohort study of clinically suspected adult dengue patients recruited from the National hospital of Sri Lanka (within the first 3 days of fever) that aimed to a) identify clinical and basic laboratory test parameters to differentiate dengue from non-d

SUBMITTER: Sigera PC 

PROVIDER: S-EPMC6676631 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature