Association between PPARG genetic polymorphisms and ischemic stroke risk in a northern Chinese Han population: a case-control study.

ABSTRACT: Two common polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARG) gene, rs1801282 and rs3856806, may be important candidate gene loci affecting the susceptibility to ischemic stroke. This case-control study sought to identify the relationship between these two single-nucleotide polymorphisms and ischemic stroke risk in a northern Chinese Han population. A total of 910 ischemic stroke participants were recruited from the First Hospital of China Medical University, Shenyang, China as a case group, of whom 895 completed the study. The 883 healthy controls were recruited from the Health Check Center of the First Hospital of China Medical University, Shenyang, China. All participants or family members provided informed consent. The study protocol was approved by the Ethic

SUBMITTER: Wang YZ 

PROVIDER: S-EPMC6676861 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature