Propensity-matched analysis of the influence of perioperative statin therapy on outcomes after liver resection.

ABSTRACT:

Background

Perioperative use of statins is reported to improve postoperative outcomes after cardiac and non-cardiovascular surgery. The aim of this study was to investigate the influence of statins on postoperative outcomes including complications of grade IIIa and above, posthepatectomy liver failure (PHLF), and 90-day mortality rates after liver resection.

Methods

Patients who underwent hepatectomy between 2013 and 2017 were reviewed to identify statin users and non-users (controls). Propensity matching was conducted for age, BMI, type of surgery and preoperative co-morbidities to compare subgroups. Univariable and multivariable analyses were performed for the following outcomes: 90-day mortality, significant postoperative complications and PHLF.

Results

Of 890 pati

SUBMITTER: Dasari BVM 

PROVIDER: S-EPMC6677106 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature