Timing and Amount of Gestational Weight Gain in Association with Adverse Birth Outcomes.

ABSTRACT:

Background

Most existing research on gestational weight gain and pregnancy outcomes has not accounted for timing of weight gain. The area under the weight gain curve (AUC) provides a single measure that incorporates both timing of weight gain and total amount gained. This study evaluated predictors and outcomes associated with second- and third-trimester weight gain AUC from the second and third trimester using time-to-event analysis to account for the correlation between gestational weight gain and gestational duration.

Methods

Our prospective cohort study used data from the LifeCodes study at Brigham and Women's Hospital. Maternal weights were available from all prenatal and study visits. We used log-Poisson models with empirical variance estimation to identify predictors

SUBMITTER: Darling AM 

PROVIDER: S-EPMC6677615 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature