Alcohol Use in Pregnancy and Miscarriage: A Systematic Review and Meta-Analysis.

ABSTRACT: To systematically review and critically evaluate studies reporting alcohol exposure during pregnancy and miscarriage. We searched PubMed, EMBASE, PsycINFO, and ProQuest Theses for publications from January 1970 to January 2019. We identified studies about alcohol exposure during pregnancy and miscarriage. Information about study population, alcohol exposure assessment, outcome definition, covariates, and measures of association was collected. We assessed study quality using an adapted Newcastle-Ottawa Scale. Data were abstracted by 2 investigators independently. We conducted a random-effects meta-analysis to calculate the association between alcohol exposure and miscarriage risk and performed subgroup analyses to determine robustness of results to study differences. For studies reporting d

SUBMITTER: Sundermann AC 

PROVIDER: S-EPMC6677630 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature