Examining resting-state functional connectivity in first-episode schizophrenia with 7T fMRI and MEG.

ABSTRACT: Schizophrenia is often characterized by dysconnections in the brain, which can be estimated via functional connectivity analyses. Commonly measured using resting-state functional magnetic resonance imaging (fMRI) in order to characterize the intrinsic or baseline function of the brain, fMRI functional connectivity has significantly contributed to the understanding of schizophrenia. However, these measures may not capture the full extent of functional connectivity abnormalities in schizophrenia as fMRI is temporally limited by the hemodynamic response. In order to extend fMRI functional connectivity findings, the complementary modality of magnetoencephalography (MEG) can be utilized to capture electrophysiological functional connectivity abnormalities in schizophrenia that are not obtainabl

SUBMITTER: Lottman KK 

PROVIDER: S-EPMC6677917 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature