Enablers and barriers to treatment adherence in heterozygous familial hypercholesterolaemia: a qualitative evidence synthesis.

ABSTRACT:

Objectives

Individuals with heterozygous familial hypercholesterolaemia (FH) are at high risk of developing cardiovascular disease (CVD). This risk can be substantially reduced with lifelong pharmacological and lifestyle treatment; however, research suggests adherence is poor. We synthesised the qualitative research to identify enablers and barriers to treatment adherence.

Design

This study conducted a thematic synthesis of qualitative studies.

Data sources

MEDLINE, Embase, PsycINFO via OVID, Cochrane library and CINAHL databases and grey literature sources were searched through September 2018.

Eligibility criteria

We included studies conducted in individuals with FH, and their family members, which reported primary qualitative data regarding their experiences

SUBMITTER: Kinnear FJ 

PROVIDER: S-EPMC6677970 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature