Antipsychotic initiation among adults with intellectual and developmental disabilities in Ontario: a population-based cohort study.

ABSTRACT:

Objectives

To describe factors associated with initiating antipsychotics and patterns of persistence to antipsychotic therapy in a large cohort of adults with intellectual and developmental disabilities.

Design

Population-based cohort study.

Setting

Ontario, Canada.

Participants

Adults with intellectual and developmental disabilities (IDD) in Ontario.

Outcome measures

We used multivariable logistic regression to investigate patient characteristics associated with antipsychotic initiation. Patient characteristics studied included sociodemographic characteristics, measures of clinical comorbidity and health service use.

Results

Among 39 244 individuals eligible for this study, 6924 (17.6%) initiated an antipsychotic over the accrual window, of whom

SUBMITTER: Gomes T 

PROVIDER: S-EPMC6677990 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature