Comparison of Glucose Tolerance between Kidney Transplant Recipients and Healthy Controls.

ABSTRACT: Post-transplant hyperglycemia and new-onset diabetes mellitus after transplantation (NODAT) are common and important metabolic complications. Decreased insulin secretion and increased insulin resistance are important to the pathophysiologic mechanism behind NODAT. However, the progression of glucose intolerance diagnosed late after kidney transplantation remains clearly unknown. Enrolled in this study were 94 kidney transplant recipients and 134 kidney transplant donors, as the healthy controls, who were treated at our institution. The 75 g-oral glucose tolerance test (OGTT) was performed in the recipients, and the healthy controls received an OGTT before donor nephrectomy. We assessed the prevalence of glucose intolerance including impaired fasting glucose and/or impaired glucose toleranc

SUBMITTER: Shimada H 

PROVIDER: S-EPMC6678426 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature