Antivirals for treatment of influenza: a systematic review and meta-analysis of observational studies.

ABSTRACT:

Background

Systematic reviews of randomized, controlled trials in patients with influenza suggest a lack of evidence about the effects of antiviral therapy on several patient-important outcomes of influenza.

Purpose

To systematically review observational studies for benefits and harms of oseltamivir, zanamivir, amantadine, or rimantadine in the treatment of influenza.

Data sources

MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, CINAHL, SIGLE, the Chinese Biomedical Literature Database, Panteleimon, and LILACS up to November 2010; contact with pharmaceutical companies; and reference lists.

Study selection

Observational studies in any language that compared single antiviral therapy with no therapy or other antiviral therapy, or that had no co

SUBMITTER: Hsu J 

PROVIDER: S-EPMC6679687 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature