Near-roadway air pollution exposure and altered fatty acid oxidation among adolescents and young adults - The interplay with obesity.

ABSTRACT:

Background

Air pollution exposure has been shown to increase the risk of obesity and metabolic dysfunction in animal models and human studies. However, the metabolic pathways altered by air pollution exposure are unclear, especially in adolescents and young adults who are at a critical period in the development of cardio-metabolic diseases.

Objectives

The aim of this study was to examine the associations between air pollution exposure and indices of fatty acid and amino acid metabolism.

Methods

A total of 173 young adults (18-23 years) from eight Children's Health Study (CHS) Southern California communities were examined from 2014 to 2018. Near-roadway air pollution (NRAP) exposure (freeway and non-freeway) and regional air pollution exposure (nitrogen dioxide, ozone

SUBMITTER: Chen Z 

PROVIDER: S-EPMC6679991 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature