Body Mass Index and Risks of Incident Ischemic Stroke Subtypes: The Japan Public Health Center-Based Prospective (JPHC) Study.

ABSTRACT:

Background

The association of body mass index (BMI) with risks of ischemic stroke subtypes have not been established.

Methods

Cumulative average BMI was calculated using self-reported body weight and height obtained from baseline (Cohort I in 1990, and Cohort II from 1993-1994) and 5- and 10-year questionnaire surveys of Japan Public Health Center-based prospective (JPHC) study. A total of 42,343 men and 46,413 women aged 40-69 years were followed-up for the incidence of lacunar, large-artery occlusive, and cardioembolic strokes. A sub-distribution hazard model was used to estimate sub-distribution hazard ratios (SHRs) and the 95% confidence intervals (CIs).

Results

During a median of 20.0 years of follow-up, we documented 809 and 481 lacunar, 395 and 218 large-artery

SUBMITTER: Li Y 

PROVIDER: S-EPMC6680058 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature