Mortality in Individuals Aged 80 and Older with Type 2 Diabetes Mellitus in Relation to Glycosylated Hemoglobin, Blood Pressure, and Total Cholesterol.

ABSTRACT:

Objectives

To evaluate whether low glycosylated hemoglobin (HbA1c), blood pressure (BP), and total cholesterol (TC) are associated with lower risk of all-cause mortality in very old individuals with type 2 diabetes mellitus.

Design

Population-based cohort study.

Setting

Primary care database in the United Kingdom.

Participants

Individuals aged 80 and older with type 2 diabetes mellitus (N = 25,966).

Measurements

Associations between baseline HbA1c, BP, and TC and all-cause mortality were evaluated in Cox proportional hazards models. Analyses were adjusted for sex, age, duration of diabetes mellitus, lifestyle variables, HbA1c, BP, TC, comorbidities, prescribing of antidiabetic and cardiovascular drugs, and participants' general practice.

Results

T

SUBMITTER: Hamada S 

PROVIDER: S-EPMC6680323 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature