Long-term follow up after endoscopic valve therapy in patients with severe emphysema.

ABSTRACT:

Background and objective

Endoscopic valve therapy is a treatment modality in patients with advanced emphysema and absent interlobar collateral ventilation (CV). So far, long-term outcome following valve implantation has been insufficiently evaluated. The aim of this study was to investigate the real-world efficacy of this interventional therapy over 3 years.

Methods

From 2006 to 2013, 256 patients with severe emphysema in whom absent CV was confirmed underwent valve therapy. The 3-year effectiveness was evaluated by pulmonary function testing (VC, FEV₁, RV, TLC), 6-minute-walk test (6-MWT) and dyspnea questionnaire (mMRC). Long-term outcome was also assessed according to the radiological outcome following valve placement.

Results

Of 256 patients treated wit

SUBMITTER: Gompelmann D 

PROVIDER: S-EPMC6681249 | biostudies-literature | 2019 Jan-Dec

REPOSITORIES: biostudies-literature