Guideline compliance for bridging anticoagulation use in vitamin-K antagonist patients; practice variation and factors associated with non-compliance.

ABSTRACT:

Background

Bridging anticoagulation is used in vitamin-K antagonist (VKA) patients undergoing invasive procedures and involves complex risk assessment in order to prevent thromboembolic and bleeding outcomes.

Objectives

Our aim was to assess guideline compliance and identify factors associated with bridging and especially, non-compliant bridging.

Methods

A retrospective review of 256 patient records in 13 Dutch hospitals was performed. Demographic, clinical, surgical and care delivery characteristics were collected. Compliance to the American College of Chest Physicians ninth edition guideline (AT9) was assessed. Multilevel regression models were built to explain bridging use and predict non-compliance.

Results

Bridging use varied from 15.0 to 83.3% (mean = 41.

SUBMITTER: Moesker MJ 

PROVIDER: S-EPMC6681479 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature