Study of VIPER and TATE in kinetoplastids and the evolution of tyrosine recombinase retrotransposons.

ABSTRACT:

Background

Kinetoplastids are a flagellated group of protists, including some parasites, such as Trypanosoma and Leishmania species, that can cause diseases in humans and other animals. The genomes of these species enclose a fraction of retrotransposons including VIPER and TATE, two poorly studied transposable elements that encode a tyrosine recombinase (YR) and were previously classified as DIRS elements. This study investigated the distribution and evolution of VIPER and TATE in kinetoplastids to understand the relationships of these elements with other retrotransposons.

Results

We observed that VIPER and TATE have a discontinuous distribution among Trypanosomatidae, with several events of loss and degeneration occurr

SUBMITTER: Ribeiro YC 

PROVIDER: S-EPMC6681497 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature