Distinction of cardiometabolic profiles among people ≥75 years with type 2 diabetes: a latent profile analysis.

ABSTRACT:

Background

Older patients with type 2 diabetes mellitus represent a heterogeneous group in terms of metabolic profile. It makes glucose-lowering-therapy (GLT) complex to manage, as it needs to be individualised according to the patient profile. This study aimed to identify and characterize subgroups existing among older patients with diabetes.

Methods

Retrospective observational cohort study of outpatients followed in a Belgian diabetes clinic. Included participants were all aged ≥75 years, diagnosed with type 2 diabetes, Caucasian, and had a Homeostasis Model Assessment (HOMA2). A latent profile analysis was conducted to classify patients using the age at diabetes diagnosis and HOMA2 variables, i.e. insulin sensitivity (HOMA2%-S), beta-cell-function (HOMA2%-β), and the prod

SUBMITTER: Christiaens A 

PROVIDER: S-EPMC6683451 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature