Ontology highlight
ABSTRACT:
SUBMITTER: Canete PF
PROVIDER: S-EPMC6683995 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
The Journal of experimental medicine 20190617 8
Mucosal lymphoid tissues such as human tonsil are colonized by bacteria and exposed to ingested and inhaled antigens, requiring tight regulation of immune responses. Antibody responses are regulated by follicular helper T (T<sub>FH</sub>) cells and FOXP3<sup>+</sup> follicular regulatory T (T<sub>FR</sub>) cells. Here we describe a subset of human tonsillar follicular T cells identified by expression of T<sub>FH</sub> markers and CD25 that are the main source of follicular T (T<sub>F</sub>) cell ...[more]