Transcriptomic differences noted in Glaesserella parasuis between growth in broth and on agar.

ABSTRACT: Glaesserella parasuis is the cause of Glӓsser's disease in pigs and is a significant contributor to post-weaning mortality in the swine industry. Prevention of G. parasuis disease relies primarily on bacterin vaccines, which have shown good homologous protection and variable heterologous protection. Bacterin production involves large scale growth of the bacteria and proteins produced during the proliferation phase of production become important antigens that stimulate the immune response. In order to evaluate genes activated during G. parasuis growth on different media substrates, the transcriptome of broth and agar grown G. parasuis strain 29755 were sequenced and compared. The transcription of most purported virulence genes were comparable between broth and agar grown G. parasuis; howeve

SUBMITTER: Hau SJ 

PROVIDER: S-EPMC6684057 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature