Trauma-associated anterior cingulate connectivity during reward learning predicts affective and anxiety states in young adults.

ABSTRACT:

Background

Trauma exposure is associated with development of depression and anxiety; yet, some individuals are resilient to these trauma-associated effects. Differentiating mechanisms underlying development of negative affect and resilience following trauma is critical for developing effective interventions. One pathway through which trauma could exert its effects on negative affect is reward-learning networks. In this study, we examined relationships among lifetime trauma, reward-learning network function, and emotional states in young adults.

Methods

One hundred eleven young adults self-reported trauma and emotional states and underwent functional magnetic resonance imaging during a monetary reward task. Trauma-associated neural activation and functional connectivity were

SUBMITTER: Eckstrand KL 

PROVIDER: S-EPMC6684106 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature