Local inhibitory plasticity tunes macroscopic brain dynamics and allows the emergence of functional brain networks.

ABSTRACT: Rich, spontaneous brain activity has been observed across a range of different temporal and spatial scales. These dynamics are thought to be important for efficient neural functioning. A range of experimental evidence suggests that these neural dynamics are maintained across a variety of different cognitive states, in response to alterations of the environment and to changes in brain configuration (e.g., across individuals, development and in many neurological disorders). This suggests that the brain has evolved mechanisms to maintain rich dynamics across a broad range of situations. Several mechanisms based around homeostatic plasticity have been proposed to explain how these dynamics emerge from networks of neurons at the microscopic scale. Here we explore how a homeostatic mechanism may

SUBMITTER: Hellyer PJ 

PROVIDER: S-EPMC6684371 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature