Evaluation of plasma arsenicals as potential biomarkers of exposure to inorganic arsenic.

ABSTRACT: Exposure to inorganic arsenic (iAs) remains a global public health problem. Urinary arsenicals are the current gold-standard for estimating both iAs exposure and iAs metabolism. However, the distribution of these arsenicals may differ between the urine and target organs. Instead, plasma arsenicals may better represent internal dose and capture target organ exposure to arsenicals. Drinking water iAs, plasma and urinary arsenicals were quantified in individuals living in the Zimapan and Lagunera regions of Mexico. The relationship between drinking water iAs and plasma arsenicals was examined using both Spearman correlations and multivariable linear regression models. In addition, the distribution of arsenicals in plasma and urine was examined and the association between plasma and urinary ar

SUBMITTER: Bommarito PA 

PROVIDER: S-EPMC6684877 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature