A medical mirroring: chronic myelomonocytic leukemia mimicking immunoglobulin G4-related disease.

ABSTRACT: Chronic myelomonocytic leukemia (CMML) can be complicated by autoimmune features associated with rheumatologic disorders, which have been commonly reported by more researches currently. The intrinsic correlation between CMML and autoimmune diseases can create significant pitfalls in differential diagnosis. CMML occasionally presents with clinical and histopathological manifestations that are similar to those of Immunoglobulin G4-related disease (IgG4-RD), a newly recognized systemic autoimmune disorder. Both CMML and IgG4-RD can have significant overlaps due to the common nature of these systemic disorders, especially when atypical clinical phenotypes are present. It is significant for physicians to accurately distinguish CMML and IgG4-RD because the therapy modalities could differ extreme

SUBMITTER: Bai Z 

PROVIDER: S-EPMC6684895 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature