Pathogenicity comparison of duck Tembusu virus in different aged Cherry Valley breeding ducks.

ABSTRACT:

Background

Although several studies have revealed that the sensitivity of ducklings to duck Tembusu virus (DTMUV) was related to age, however, DTMUV was originally isolated from egg-laying ducks, and the ovary was the target organ of this virus. Cherry Valley breeding ducks aged 15- and 55-week-old (they are reserve breeding ducks and the normal egg-laying breeding ducks, respectively) were infected with DTMUV, using intramuscular injection, to study the effect of age-related difference on the pathogenicity of DTMUV in breeding ducks.

Results

Examinations of clinical symptoms, gross and microscopic lesions, viral loads, cytokines and serum neutralizing antibodies were performed. Results showed that obvious clinical symptoms, such as depression, ruffled feathers, ataxia and e

SUBMITTER: Lv C 

PROVIDER: S-EPMC6685157 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature