Establishing the interchangeability of arterial stiffness but not endothelial function parameters in healthy individuals.

ABSTRACT:

Background

Development of instruments capable of detecting early stage vascular disease has increased interest in employing arterial stiffness (e.g. pulse wave velocity (PWV), augmentation index (AIx)) and endothelial dysfunction (e.g. reactive hyperemia index (RHI)) to diagnose atherosclerotic disease before occurrence of a cardiovascular event. However, amongst the equipment designed for this purpose, there is insufficient information regarding each of these parameters to establish appropriate cutoffs to distinguish between healthy and unhealthy blood vessels. To address these limitations, the study was designed to establish the upper arterial stiffness and endothelial function thresholds in a healthy population, by comparing the outputs from different instruments capable of meas

SUBMITTER: Perrault R 

PROVIDER: S-EPMC6685177 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature