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The Association Between Novel Biomarkers and 1-Year Readmission or Mortality After Cardiac Surgery.


ABSTRACT:

Background

Novel cardiac biomarkers including soluble suppression of tumorigenicity 2, galectin-3, and the N-terminal prohormone of brain natriuretic peptide may be associated with long-term adverse outcomes after cardiac surgery. We sought to measure the association between cardiac biomarker levels and 1-year hospital readmission or mortality.

Methods

Plasma biomarkers from 1,047 patients discharged alive after isolated coronary artery bypass graft surgery from 8 medical centers were measured in a cohort from the Northern New England Cardiovascular Disease Study Group between 2004 and 2007. We evaluated the association between preoperative and postoperative biomarkers and 1-year readmission or mortality using Kaplan-Meier estimates and Cox proportional hazards modeling, adj

SUBMITTER: Jacobs JP 

PROVIDER: S-EPMC6685203 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature