Left ventricular ejection time is an independent predictor of incident heart failure in a community-based cohort.

ABSTRACT:

Aims

Systolic time intervals change in the progress of cardiac dysfunction. The usefulness of left ventricular ejection time (LVET) to predict cardiovascular morbidity, however, is unknown.

Methods and results

We studied middle-aged African-Americans from one of four cohorts of the Atherosclerosis Risk in Communities study (Jackson cohort, n=1980) who underwent echocardiography between 1993 and 1995. Left ventricular ejection time was measured by pulsed-wave Doppler of the left ventricular outflow tract and related to outcomes. A shorter LVET was associated with younger age, male sex, higher diastolic blood pressure, higher proportion of diabetes, higher heart rate, higher blood glucose levels and worse fractional shortening. During a median follow-up of 17.6 years, 384 (19%

SUBMITTER: Biering-Sorensen T 

PROVIDER: S-EPMC6685547 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature