Multiscale model of regional population decline in little brown bats due to white-nose syndrome.

ABSTRACT: The introduced fungal pathogen Pseudogymnoascus destructans is causing decline of several species of bats in North America, with some even at risk of extinction or extirpation. The severity of the epidemic of white-nose syndrome caused by P. destructans has prompted investigation of the transmission and virulence of infection at multiple scales, but linking these scales is necessary to quantify the mechanisms of transmission and assess population-scale declines.We built a model connecting within-hibernaculum disease dynamics of little brown bats to regional-scale dispersal, reproduction, and disease spread, including multiple plausible mechanisms of transmission.We parameterized the model using the approach of plausible parameter sets, by comparing stochastic simulation resul

SUBMITTER: Kramer AM 

PROVIDER: S-EPMC6686297 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature