Health-related quality of life and its risk factors in Chinese hereditary angioedema patients.

ABSTRACT:

Background

Hereditary angioedema (HAE) is a rare but serious condition characterized by unpredictable and recurrent attacks affecting the skin and mucosa. HAE has wide-ranging impacts on the health-related quality of life (HRQoL) of patients. This study aims to assess the HRQoL of Chinese patients with HAE using the 36-item Short Form Health Survey (SF-36v2) and to explore potential risk factors for low HRQoL.

Methods

A total of 104 patients (47 male and 57 female) over age 18 living in China with a known diagnosis of HAE due to C1-INH deficiency completed the SF-36v2 (generic HRQoL questionnaire). The results were compared to Chinese population norms. Subgroup analysis and logistic regression were used to interpret the data.

Results

SF-36v2 showed a significant reduc

SUBMITTER: Liu S 

PROVIDER: S-EPMC6686410 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature