Racial disparities in end-stage renal disease in a high-risk population: the Southern Community Cohort Study.

ABSTRACT:

Introduction

The Southern Community Cohort Study is a prospective study of low socioeconomic status (SES) blacks and whites from the southeastern US, where the burden of end-stage renal disease (ESRD) and its risk factors are high. We tested whether the 2.4-fold elevated risk of ESRD we previously observed in blacks compared to whites was explained by differences in baseline kidney function.

Methods

We conducted a case-cohort study of incident ESRD cases (n = 737) with stored blood and a probability sampled subcohort (n = 4238) and calculated estimated glomerular filtration rate (eGFR) from serum creatinine. 86% of participants were enrolled from community health centers in medically underserved areas and 14% from the general population in 12 states in the southeastern Unite

SUBMITTER: Bock F 

PROVIDER: S-EPMC6686512 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature