Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution.

ABSTRACT:

Background

Angiosarcoma is an uncommon endothelial malignancy and a highly aggressive soft tissue sarcoma. Due to its infiltrative nature, successful management of localized angiosarcoma is often challenging. Systemic chemotherapy is used in the metastatic setting and occasionally in patients with high-risk localized disease in neoadjuvant or adjuvant settings. However, responses tend to be short-lived and most patients succumb to metastatic disease. Novel therapies are needed for patients with angiosarcomas.

Methods

We performed a retrospective analysis of patients with locally advanced or metastatic angiosarcoma, who were treated with checkpoint inhibitors at our institution. We collected their clinical information and outcome measurements. In one patient with achieved com

SUBMITTER: Florou V 

PROVIDER: S-EPMC6686562 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature