Perioperative Management of Patients With Atrial Fibrillation Receiving a Direct Oral Anticoagulant.

ABSTRACT:

Importance

Patients with atrial fibrillation (AF) who use a direct oral anticoagulant (DOAC) and request elective surgery or procedure present a common clinical situation yet perioperative management is uncertain.

Objective

To investigate the safety of a standardized perioperative DOAC management strategy.

Design, setting, and participants

The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) cohort study conducted at 23 clinical centers in Canada, the United States, and Europe enrolled and screened patients from August 1, 2014, through July 31, 2018. Participants (n = 3007) had AF; were 18 years of age or older; were long-term users of apixaban, dabigatran etexilate, or rivaroxaban; were scheduled for an elective surgery or procedure; and could adhere

SUBMITTER: Douketis JD 

PROVIDER: S-EPMC6686768 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature