Hormone receptor expression of colorectal cancer diagnosed during the peri-partum period.

ABSTRACT:

Background

Colorectal carcinoma (CRC) during the peri-partum period is challenging to diagnose due to the overlapping symptoms of CRC and pregnancy. This is the first case series to investigate clinicopathologic, hormonal and molecular features of CRC diagnosed during the peri-partum period. We hypothesized that advanced presentations of CRC could possibly be mitigated by pregnancy-related hormonal factors.

Methods

We conducted a retrospective review of five women diagnosed with CRC during the peri-partum period and studied the clinical and molecular features of their cancer.

Results

All patients presented with stage IV CRC at diagnosis; three had primary tumors in the rectum and two had primary tumors in the sigmoid colon. The liver was the most common metastatic sit

SUBMITTER: Silverstein J 

PROVIDER: S-EPMC6686950 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature