Association between LKB1 expression and prognosis of patients with solid tumours: an updated systematic review and meta-analysis.

ABSTRACT:

Objectives

Liver kinase B1 (LKB1) is considered a tumour suppressor that can control cell growth and metabolism. Whether LKB1 expression levels are related to clinicopathology and prognosis is controversial. This review aimed to quantitatively examine the latest evidence on this question.

Design

An updated systematic review and meta-analysis on the association between LKB1 expression and prognosis of patients with solid tumours were performed.

Data sources

Eligible studies were identified through literature searches from database establishment until 15 June 2018 in the following databases: Embase, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure and Wan Fang databases.

Eligibility criteria

The association between LKB1 expression

SUBMITTER: Ren YH 

PROVIDER: S-EPMC6687027 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature