Allelic variation in a single genomic region alters the hemolymph proteome in the snail Biomphalaria glabrata.

ABSTRACT: Freshwater snails are obligate intermediate hosts for numerous parasitic trematodes, most notably schistosomes. Schistosomiasis is a devastating human and veterinary illness, which is primarily controlled by limiting the transmission of these parasites from their intermediate snail hosts. Understanding how this transmission occurs, as well as the basic immunobiology of these snails may be important for controlling this disease in the future. Allelic variation in the Guadeloupe resistance complex (GRC) of Biomphalaria glabrata partially determines their susceptibility to parasitic infection, and can influence the microbiome diversity and microbial defenses in the hemolymph of these snails. In the present study, we examine the most abundant proteins present in the hemolymph of snails that ar

SUBMITTER: Allan ERO 

PROVIDER: S-EPMC6687060 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature