Smear positive tuberculosis and genetic diversity of M. tuberculosis isolates in individuals visiting health facilities in South Gondar Zone, northwest Ethiopia.

ABSTRACT:

Background

Tuberculosis (TB), a bacterial infectious disease, continues to be a public health concern in many developing countries. However, lack of data concerning the public health burden and potential risk factors for the disease hampers control programs in target areas. Therefore, the aims of present study were to determine the prevalence of TB and genetic diversity of M. tuberculosis isolates from individuals visiting health facilities in South Gondar Zone, northwest Ethiopia.

Methods

A cross-sectonal study was conducted between March 2015 and April 2017. Bacteriological examination, region of difference (RD) 9 based polymerase chain reaction (PCR) and spoligotyping were used.

Results

The overall prevalence of all smear positive TB was 6.3% (186/2953). Extra pulm

SUBMITTER: Alelign A 

PROVIDER: S-EPMC6687116 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature