Stillbirth and associated perinatal outcomes in obstetric cholestasis: a systematic review and meta-analysis of observational studies.

ABSTRACT:

Background

Obstetric cholestasis is a condition occurring in pregnancy with suspected adverse perinatal outcomes. Stillbirth is a significant adverse event associated with obstetric cholestasis and considered for intervention in pregnancy.

Objectives

There are multiple studies with epidemiological data with regards to the outcomes of obstetric cholestasis. Our hypothesis is to the test the association of stillbirth and related outcomes in obstetric cholestasis.

Search strategy & selection criteria

Two independent reviewers did independent searches and selection with a standardized design as outlined in the PRISMA statement.

Analysis

The retrieved relevant literature was subjected to a rigorous quality assessment and followed by standardized interpretable result

SUBMITTER: Mohan M 

PROVIDER: S-EPMC6687374 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature