Does polycystic ovary syndrome affect morphokinetics or abnormalities in early embryonic development?

ABSTRACT:

Objectives

This study aimed to investigate whether oocyte retrieval from PCOS patients affects the morphokinetics or the incidence of abnormalities in early embryonic development, using time-lapse imaging analysis.

Methods

This was a prospective study in total of 39 PCOS patients and 67 women with normal ovarian function, underwent a GnRH antagonist protocol of controlled ovarian stimulation and fertilization by ICSI. 402 zygotes from the PCOS group and 449 zygotes from the control group were observed by time-lapse monitoring for 48 h following sperm injection.

Results

Patients with PCOS showed a significantly higher number of retrieved oocytes, and a significantly higher number of metaphase II oocytes per cycle than that of the non-PCOS group (18.85 ± 9.41 vs. 11.48 

SUBMITTER: Tam Le M 

PROVIDER: S-EPMC6687388 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature