Ocular adhesives: Design, chemistry, crosslinking mechanisms, and applications.

ABSTRACT: Closure of ocular wounds after an accident or surgery is typically performed by suturing, which is associated with numerous potential complications, including suture breakage, inflammation, secondary neovascularization, erosion to the surface and secondary infection, and astigmatism; for example, more than half of post-corneal transplant infections are due to suture related complications. Tissue adhesives provide promising substitutes for sutures in ophthalmic surgery. Ocular adhesives are not only intended to address the shortcomings of sutures, but also designed to be easy to use, and can potentially minimize post-operative complications. Herein, recent progress in the design, synthesis, and application of ocular adhesives, along with their advantages, limitations, and potential are disc

SUBMITTER: Trujillo-de Santiago G 

PROVIDER: S-EPMC6687460 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature