Incidence, prevalence, and outcome of primary biliary cholangitis in a nationwide Swedish population-based cohort.

ABSTRACT: Available epidemiological data on primary biliary cholangitis (PBC) in Sweden originate from regional studies in the 1980s and may not reflect modern day PBC. We aimed to estimate incidence and prevalence, survival and death causes, and gender differences in PBC. We used international classification of disease (ICD) codes to identify patients with PBC in inpatient and outpatient registries 1987-2014 who were then linked to the Swedish cause of death, cancer and prescribed drug registries. Each PBC patient was matched with 10 reference individuals from the general population. In sensitivity analyses, we examined PBC patients identified through clinical patient records from Karolinska, Sahlgrenska and Örebro University Hospitals. We identified 5,350 adults with PBC. Prevalence of PBC increas

SUBMITTER: Marschall HU 

PROVIDER: S-EPMC6687809 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature