Polygenic risk-stratified screening for cancer: Responsibilization in public health genomics.

ABSTRACT: In this article, we examine professional discourse around the development of polygenic risk-stratified screening (PRSS) for cancer. Analyzing a range of contemporary professional literatures from Europe, North America and Australia, we explore how the drive to screen for molecular markers of cancer risk makes professionals, screening recipients and publics responsible, in different ways, for acquiring, curating and analyzing molecular data. Investigating how these responsibilities are invoked in discussions of new data practices, technologies, organizational arrangements, engagement, education and protocols for participation, we argue that agendas for PRSS for cancer are both expanding and stratifying responsibilities. Data collection is to be achieved by intensified responsibilities for i

SUBMITTER: Kerr A 

PROVIDER: S-EPMC6688132 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature