Association between fluid overload and SOFA score kinetics in septic shock patients: a retrospective multicenter study.

ABSTRACT:

Background

Fluid infusion represents one of the cornerstones of resuscitation therapies in order to increase oxygen delivery during septic shock. Fluid overload as a consequence of excessive fluid administration seems to be linked to worse long-term outcome. However, its immediate effect on patient's clinical state is poorly described. The goal of this study was to assess the impact of FO on SOFA score kinetics as a surrogate marker of organ dysfunction from day 0 to day 5.

Material and methods

Retrospective, multicenter, investigator-initiated study. All adult patients (> 18 years old) admitted from January 2012 to April 2017 in one of the three ICUs for septic shock, secondary to peritonitis or pulmonary infection and mechanically ventilated, were included. Univariate anal

SUBMITTER: Chapalain X 

PROVIDER: S-EPMC6688320 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature