Stimulant medication and substance use outcomes: a meta-analysis.

ABSTRACT:

Importance

Psychostimulant medication is an efficacious treatment for childhood attention-deficit/hyperactivity disorder, yet controversy remains regarding potential iatrogenic effects of stimulant medication, particularly with respect to increasing susceptibility to later substance use disorders. However, stimulant treatment was previously reported to reduce the risk of substance problems.

Objective

To meta-analyze the longitudinal association between treatment with stimulant medication during childhood and later substance outcomes (ie, lifetime substance use and substance abuse or dependence).

Data sources

Studies published between January 1980 and February 2012 were identified using review articles, PubMed, and pertinent listservs.

Study selection

Studies wi

SUBMITTER: Humphreys KL 

PROVIDER: S-EPMC6688478 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature