Frontoinsular Network Markers of Current and Future Adolescent Mood Health.

ABSTRACT:

Background

Adolescence is a developmental period in which depression and related mood syndromes often emerge, but few objective markers exist to guide diagnosis or predict symptoms. One potential mood marker is the functioning of frontoinsular networks, which undergo substantial development in adolescence and have been implicated in adult depression. To test this hypothesis, we used task-based neuroimaging to evaluate whether frontoinsular network dysfunction was linked to current and prospective mood health in adolescents.

Methods

Adolescents (n = 40, 13-19 years of age) reporting varying levels of depressive symptom severity performed an emotional working memory task with neuroimaging. Next, teens completed a 2-week follow-up consisting of a daily diary report of negative

SUBMITTER: Kaiser RH 

PROVIDER: S-EPMC6688954 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature