Intake of Trace Metals and the Risk of Incident Kidney Stones.

ABSTRACT:

Purpose

The association between the intake of trace metals and the risk of incident stones has not been longitudinally investigated.

Materials and methods

We performed a prospective analysis of 193,551 participants in the Health Professionals Follow-up Study, and the Nurses' Health Study I and II. During a followup of 3,316,580 person-years there was a total of 6,576 incident stones. We used multivariate regression models to identify associations of the intake of zinc, iron, copper and manganese with the risk of stones. In a subset of participants with 24-hour urine collections we examined the association between the intake of trace metals and urine composition.

Results

After multivariate adjustment total and dietary intakes of zinc and iron were not significantly ass

SUBMITTER: Ferraro PM 

PROVIDER: S-EPMC6689148 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature