Resting Oxygen Consumption and Heart Failure: Importance of Measurement for Determination of Cardiac Output With the Use of the Fick Principle.

ABSTRACT:

Background

Resting oxygen consumption (VO₂) is often estimated and frequently used to guide therapeutic decisions in symptomatic heart failure (HF) patients. The relationship between resting VO₂ and symptomatic HF and the accuracy of estimations of VO₂ in this population are unknown.

Methods and results

We performed a cross-sectional study of HF patients (n = 691) and healthy control subjects (n = 77). VO₂ was measured with the use of a metabolic cart, and estimated VO₂ was calculated with the use of the Dehmer, LaFarge, and Bergstra formulas and the thermodilution method. The measured and estimated VO₂ were compared and the potential impact of estimations determined. In the multivariable model, resting VO

SUBMITTER: Grafton G 

PROVIDER: S-EPMC6689258 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature