Peri-Coronary Adipose Tissue Density Is Associated With ¹⁸F-Sodium Fluoride Coronary Uptake in Stable Patients With High-Risk Plaques.

ABSTRACT:

Objectives

This study aimed to assess the association between increased lesion peri-coronary adipose tissue (PCAT) density and coronary ¹⁸F-sodium fluoride (¹⁸F-NaF) uptake on positron emission tomography (PET) in stable patients with high-risk coronary plaques (HRPs) shown on coronary computed tomography angiography (CTA).

Background

Coronary ¹⁸F-NaF uptake reflects the rate of calcification of coronary atherosclerotic plaque. Increased PCAT density is associated with vascular inflammation. Currently, the relationship between increased PCAT density and ¹⁸F-NaF uptake in stable patients with HRPs on coronary CTA has not been characterized.

Methods

Patients who underwent coronary CTA were screened for HRP, which was defined b

SUBMITTER: Kwiecinski J 

PROVIDER: S-EPMC6689460 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature