Risk Factors for Late-Onset Sepsis in Preterm Infants: A Multicenter Case-Control Study.

ABSTRACT:

Background

Late-onset sepsis (LOS) in preterm infants is a leading cause of mortality and morbidity. Timely recognition and initiation of antibiotics are important factors for improved outcomes. Identification of risk factors could allow selection of infants at an increased risk for LOS.

Objectives

The aim was to identify risk factors for LOS.

Methods

In this multicenter case-control study, preterm infants born at ≤30 weeks of gestation were included at 9 neonatal intensive care units. Detailed demographical and clinical data were collected daily up to day 28 postnatally. Clinical and demographic risk factors were identified using univariate and multivariate regression analyses in a 1: 1 matched case-control cohort.

Results

In total, 755 infants were included,

SUBMITTER: El Manouni El Hassani S 

PROVIDER: S-EPMC6690411 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature