Longitudinal analysis of risk factors for dementia based on Mild Cognitive Impairment Screen results and questionnaire responses from healthy Japanese individuals registered in an online database.

ABSTRACT:

Introduction

Despite an urgent need for developing remedial measures against dementia, no disease-modifying drugs have been developed. Efficient protocols for participant recruitment need to be established for conducting clinical trials. To meet this need, a large-scale online registry system, the Integrated Registry of Orange Plan (IROOP^®), was created for healthy individuals. Although the risk factors for dementia have been discussed in our previous studies for a short interval of 6 months, some factors remain controversial. The present study aimed to explore factors affecting longitudinal changes in cognitive function for a longer interval of 18 months using the IROOP^® data.

Methods

This study assessed the longitudinal changes in the collated data fo

SUBMITTER: Ogawa M 

PROVIDER: S-EPMC6690416 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature